The next Google

first_img <a href=”https://www.youtube.com/watch?v=9-154kFb0BM” rel=”nofollow” target=”_blank”> <img src=”https://img.youtube.com/vi/9-154kFb0BM/0.jpg” alt=”0″ title=”How To Choose The Correct Channel Type For Your Video Content ” /> </a> How does our educational system prepare the next generation of students for living and working in the digital age? Try giving out free pizza.Learning to use analytical skills to measure and solve problems is an essential life skill in the coming era, one that every major university should be — but isn’t necessarily — teaching students, said Eric Schmidt, Google’s longtime CEO, and now its executive chairman. All that would be needed to jumpstart that process is to gather smart young people interested in entrepreneurship in a room together for pizza and get them talking to each other.“Because that’s how people learn,” he said. “The sense of being in the middle of something great is hugely motivating to people who want to start new things.”In order to create another “hive of knowledge” like Silicon Valley, cities need to reproduce key elements that seem to make everything work, like a stable base of venture capital, weak employment contract laws, a culture of sharing, and a steady supply of very smart people flowing in and out, said Schmidt. But it’s a tall order.“Here in Cambridge, we have some of the smartest people in the world … If I can be critical for a sec: Why have you guys not produced the equivalent of Twitter, Facebook, Google, and so forth? I don’t know,” he said. “So there’s an action item for you.” His comments reflected the corporate reality, though the key founders of both Microsoft and Facebook were former Harvard College students.Schmidt’s remarks came Thursday evening during a wide-ranging talk about leadership, innovation, and entrepreneurship at the Harvard Kennedy School (HKS), a session sponsored by the Institute of Politics with moderator David Gergen, co-director of the Center for Public Leadership, and an introduction by HKS Dean David Ellwood.Schmidt defined entrepreneurs as confident, often young visionaries able to see what others cannot and who neither suffer fools gladly nor want for self-confidence.“We need to celebrate these people, we need to find them, and if you’re not like that, you need to befriend them because you’re going to work for them, so be nice to them,” he told students. He said they also don’t wilt in the face of adversity.“The successful entrepreneur doubles down, fights harder, leads harder, challenges harder, and eventually wins. The unsuccessful entrepreneur gets scared, gets tentative, loses confidence, falls apart,” Schmidt said. “That’s the difference between $1 billion and zero.”A C-level executive at Novell and Sun Microsystems before joining Google in 2001, Schmidt said the key to leadership, besides a sense of humor, a taste for risk, and a tolerance of failure, is to surround yourself with bright people and let them create.“I think it’s important that you recognize that you’re not actually doing the work that other people are, that your job is to understand what they’re doing, to get the strategy right and empower them. Most of the problems that companies get into … is the failure of strategy,” he said, adding, “The job of a leader is to call back and say: What are we going to do about this and keep people’s noses to fixing it.”Schmidt challenged HKS students to solve the nation’s employment problem as a pathway to relieving a host of other societal ills, such as crime and health, and he urged those studying foreign policy to apply mathematical laws used frequently in the digital world to identify and reconsider the connection and relationships within a handful of centers around the world.Taking to task what he termed the inefficiencies of most nonprofits and NGOs, Schmidt called for more innovation.“The thing I would tell you about nonprofits is that they’re full of extremely well-meaning people who need to build things,” he said, referring to online platforms that can deliver services. “There’s so much waste in the philanthropic world because they don’t measure their outcomes. We’ve asked them the basic questions. How many of this did you save? How much of this? And they can’t answer them. That’s an indication of poor management in need of better tools.”Eric Schmidt in conversation with David Gergenlast_img read more

Michigan’s Presque Isle Coal Plant to Close in 2020

first_img FacebookTwitterLinkedInEmailPrint分享The Mining Journal:The Presque Isle Power Plant is on track to close in 2020, officials say. The closing date of the coal-fired plant was confirmed at the Upper Peninsula Energy Summit Wednesday at Northern Michigan University.The facility will be replaced by two new natural gas-fueled power plants in Marquette and Baraga counties to be owned and operated by Upper Michigan Energy Resources Corp. The plants were approved by the Michigan Public Service Commission in October. The $275 million project will be capable of generating a combined 183 megawatts of power and both plants are expected to be completed by the middle of 2019.MPSC Chairwoman Sally Talberg said three new natural gas pipelines were also approved in the Upper Peninsula. Two of the pipelines will feed the new UMERC generation facilities, Talberg said, with a third project consisting of a 43-mile natural gas pipeline, to be operated by Semco Energy Gas Company, between Wells Township and Marquette, which was approved by the MPSC in August.She said the pipelines, because they would be looped — which means two or more pipelines running parallel to each other — would also address vulnerabilities in natural gas service in the U.P. and could also encourage economic development.More: Energy Summit: Officials Talk Plans and Improvements Michigan’s Presque Isle Coal Plant to Close in 2020last_img read more

HHS funds work on dose-sparing H5N1 vaccines

first_img See also: The $14.4 million award to Iomai is intended to support completion of phase 1 clinical trials of a candidate vaccine with adjuvant, according to HHS. The company “may receive an additional $114 million in funding upon successful completion of the phase 1 trials.” The Novartis contract will help the company bring its MF59 adjuvant, used in seasonal flu vaccines for elderly people in Europe, to the United States, the company said. Iomai will use the funds to develop an adjuvant skin patch to be used with flu vaccines, while a GSK news release said only that the money would be used for an “innovative adjuvant technology.” GSK will use the HHS contract to conduct “research and development leading towards licensure of antigen-sparing prepandemic and pandemic vaccines with adjuvant” to protect more people, according to a company statement. The contract gives HHS the option to provide another $44 million for “future clinical development programs” for antigen-sparing vaccines, the company said. Hall said the company’s H5N1 vaccine is egg-based. In July 2006 GSK reported that in a clinical trial, an H5N1 vaccine coupled with the company’s adjuvant triggered a good immune response with only 3.8 micrograms (mcg) of antigen, as compared with 15 mcg of antigen in a typical dose of seasonal flu vaccine (for one flu strain). As noted in today’s HHS statement, early trials of the (unadjuvanted) H5N1 vaccine in the current stockpile showed that it took two 90-mcg doses to induce what was considered a protective immune response. The patch is applied to the skin over the site of vaccination, the company said. “Once the patch is applied, the adjuvant passes into the skin, targeting cells called Langerhans cells. Those specialized skin cells carry the adjuvant to the lymph nodes, where it works to boost an individual’s immune response to the vaccine.” The Department of Health and Human Services (HHS) awarded a 5-year, $63.3 million contract to British-based GlaxoSmithKline (GSK) and a 5-year, $54.8 million contract to Swiss-based Novartis. In addition, Iomai Corp., Gaithersburg, Md., received a $14.4 million, 15-month contract, which could lead to an additional $114 million award, HHS announced in a news release. The aim of the contracts, HHS said, is to put each company in a position to produce, within 6 months after the emergence of a flu pandemic, either 150 million doses of an adjuvant-based pandemic vaccine or enough adjuvant for 150 million doses of such a vaccine. “The contracts also require each company to provide its proprietary adjuvant for U.S. Government–sponsored, independent evaluation with influenza vaccines from other manufacturers,” HHS said. “If we actually had licensed cell-based vaccines with an immunogenic adjuvant, it would put us in a much better position in the US to respond to pandemic influenza,” Osterholm said. The Novartis vaccine Fluad, which contains MF59, is licensed in Europe for preventing seasonal flu in people aged 65 and older, the company said. It said many studies have shown that the vaccine induced stronger antibody responses in elderly people than were seen with an unadjuvanted vaccine. In a news release, Novartis officials said their contract will be used to test the safety and effectiveness of the MF59 adjuvant in a pandemic flu vaccine and to support work on an MF59 production facility in Holly Springs, N.C. The vaccine will be grown in cell culture rather than in eggs. In May 2006 the company received an HHS contract to develop a cell-culture-based flu vaccine and a manufacturing facility for it. Jan 17 HHS news releasehttp://www.hhs.gov/news/press/2007pres/01/20070117b.html Jan 17 Novartis news releasehttp://cws.huginonline.com/N/134323/PR/200701/1098644_5.html With current technology, it would take about 6 months to start producing a vaccine well matched to the pandemic strain, HHS spokesman Bill Hall noted. “By having an adjuvant you can rapidly extend the number of people you can cover early on with vaccine,” he told CIDRAP News. Jan 17, 2007 (CIDRAP News) – In an effort to stretch the nation’s supply of vaccines for a potential influenza pandemic, federal health officials today announced contracts totaling $132.5 million to help three companies develop dose-sparing substances, or adjuvants, to be used with H5N1 flu vaccines. He also expressed gratification that the Novartis contract will support development of a cell-based vaccine. Cell-based production “will definitely shave time off the production of the [pandemic] vaccine,” although the pandemic strain will have to be identified first, he said. Nov 20, 2006, CIDRAP News story “HHS awards 3 contracts for more H5N1 vaccine” Michael T. Osterholm, PhD, MPH, director of the University of Minnesota Center for Infectious Disease Research and Policy, publisher of the CIDRAP Web site, praised HHS for awarding the contracts. “Adjuvants likely will play an important role in extending the number of doses that will be available once a pandemic strain is identified and vaccine production begins,” he said. Novartis said several published studies have indicated that MF59 may reduce the amount of antigen needed in H5N1 vaccines and may help such vaccines provide cross-protection against slightly different, or “drifted,” strains of the virus. An Iomai news release said the additional funding is the estimated amount needed to bring the combination of vaccine and dose-sparing patch to licensure. If the H5N1 avian flu virus evolves into a pandemic strain, vaccines are expected to be in extremely short supply. HHS is stockpiling H5N1 vaccines, but in November the stockpile amounted to enough for only about 3 million people. And no one knows how effective the vaccines will be against an emerging pandemic strain. Hence HHS is funding efforts to make vaccine supplies stretch further and to produce vaccines faster than with the conventional method of growing them in chicken eggs. Jul 26, 2006, CIDRAP News story “Glaxo says its H5N1 vaccine works at low dose”last_img read more

Wenger never gave up on Bendtner

first_img Bendtner, however, is now set for a spell on the sidelines having sprained his ankle in scoring the goal which Wenger believes was reward for his positive attitude since returning to the first-team picture this season. “Nicklas is a player who has gone through some difficult periods, so I just want to give him great credit,” said Wenger, who was already without lead striker Olivier Giroud because of his own ankle problem. “I told him already today that he is back to the level I want him to be at, and if he continues to develop like that he will come back into the team. “Unfortunately he got injured today. He was a bit unlucky, he said he landed on the foot of a Cardiff player and sprained his ankle. It looks like it is not a question of days, but weeks. “I am very sad for us, but for him as well.” Bendtner, 25, has endured a testing spell of his career, with unsuccesful loans at the likes of Sunderland and Juventus before seeing hopes of a move to Crystal Palace on transfer deadline day fail to materialise, often becoming a focal point for fans’ frustrations. Wenger continued: “I never give up on people because you always have to give them credit. “I know the expression of the fans is only the diagnosis of the day – they are always ready to change their mind if you put the effort and the performance in.” Bendtner is out of contract at the end of the season, and so could now sign an agreement to move abroad as a free agent. Wenger said: “It is January 1 so we cannot stop him [talking to clubs abroad], but he says he wants to stay here. “If he is focused on staying with us and his job, he is a great striker.” The Gunners boss maintains he will wait to decide how he tackles the January sales, with the squad in need of some attacking reinforcements. “I don’t know, it doesn’t mean we go straight from Nicklas’ ankle straight to the transfer market,” Wenger said. Wenger felt his side showed great character to finally break Cardiff’s determined resistance. He said: “It looked like in the last 25 minutes like the goal was coming, but sometimes it doesn’t – and not only does it not come but you are then caught on the counter-attack. “We needed resilience and intelligence not to make a mistake at the back and continue to go forward. In the end, Nicklas got us great relief.” Wenger revealed scans on Mesut Ozil’s shoulder problem showed “no big damage”. He said: “I believe Ozil will be short for Saturday (against Tottenham in the FA Cup) and should be ready for Aston Villa (on January 13).” Arsenal are now a point ahead of Manchester City once again, with Chelsea also having won on New Year’s Day, as did Liverpool. Wenger said: “We have a good togetherness in the side, the players come on with the right attitude and that makes the difference. “You know that if you do not have that in the championship, then you have no chance to do it. “We have that in the squad, we have to take care of that spirit and show it in every game.” For Cardiff, all the uncertainty off the pitch has not helped produce results, with the defeat at Arsenal making it just one victory from 10 league matches. Caretaker manager David Kerslake said: “We knew coming here, they have got wonderful talented players and that we would be put under the kosh, but you saw the discipline of the side, the way they defended for each other I thought we were going to hang on.” Arsenal manager Arsene Wenger maintained he had never given up on Nicklas Bendtner after the Denmark striker netted a late goal to help beat managerless Cardiff 2-0 at the Emirates Stadium, but is now set to be sidelined for few weeks with an ankle injury. Press Association It had looked like the Bluebirds, with potential new boss Ole Gunnar Solskjaer watching from the stands, would hold out for a much-needed point in the wake of relentless Arsenal pressure. However, with just two minutes left, substitute Bendtner crashed the ball in from close range after David Marshall had saved Bacary Sagna’s header before, in stoppage time, Theo Walcott sealed the victory which took the Gunners back to the top of the Barclays Premier League table. last_img read more

Friday evidence deadline for gambling’s social and economic Select Committee

first_img Winning Post: Swedish regulator pushes back on ‘Storebror’ approach to deposit limits August 24, 2020 Share Submit StumbleUpon Industry stakeholders are reminded that they have only one week to return submissions of evidence (deadline Friday 6 September) to the Select Committee researching the ‘social and economic impacts of the gambling industry’ on UK society.Announced this July, the House of Lords established a Select Committee seeking to gain ‘research insights and valuable facts’ on the UK gambling sector and its impact on individuals affected by gambling disorders.The Select Committee is led by Lord Grade of Yarmouth, who leading the inquiry underlined the need for concrete evidence from a wide range of organisations, aiding future policy development on gambling, improving standards and regulatory oversight for the sectors diverse stakeholders.Calling for greater evidence, the Committee seeks to assess a number of factors that may have been undermined by a ‘lack of accurate estimates of the extent of the problem’.Within its remit, the inquiry will review ‘the current state of the UK gambling industry’ and its contribution towards research, education, and the treatment of problem gamblers.The Committee’s call for evidence seeks insights on key criteria related to governing UK gambling, which include whether Gambling Act 2005 has achieved the aim of ‘preventing gambling from becoming a crime or disorder’.Further assessments will be made on whether UK gambling laws need to be updated to reflect significant changes in technology, and whether licensed operators have a legal duty of care towards their customers. Share UKGC hails ‘delivered efficiencies’ of its revamped licence maintenance service  August 20, 2020 Related Articles UKGC launches fourth National Lottery licence competition August 28, 2020last_img read more

WATCH: Jorge Masvidal in fist fight with Leon Edwards after win over Darren Till

first_imgDuring the middle of a question from a reporter, Masvidal actually stopped and addressed fellow welterweight Leon Edwards who was off screen.He can be heard saying, “Maybe, maybe not…hey, come over here and say it to my face.”He then walked over to Edwards and almost immediately started exchanging punches with him.It was truly bizarre scene.OMG pic.twitter.com/yVDoMG0czq— Jed I. Goodman (@jedigoodman) March 16, 2019Masvidal, 34, broke a two-fight losing streak with his win over Till. Jorge Masvidal’s night did not end with a knockout victory over Darren Till at UFC London on Saturday.After Masvidal finished the welterweight title contender in the second round, he was doing interviews soon after in the locker room. Edwards took home a split-decision win over Gunnar Nelson during an earlier fight on the night.After his win he said he should get the winner of Till-Masvidal.We’re guessing he didn’t mean immediately after the card concluded.last_img read more